Special gene increases the risk of heart disease in women

Study: Causes of heart disease in women and men differently
Scientists have discovered in women a gene that could be responsible for an increased risk of heart disease. A recent study shows that women who have a specific version of the "BCAR1" gene in their body more often suffer a heart attack or stroke. In contrast, men with the gene do not have an increased risk. There are clear differences in the causes of heart disease between women and men, according to researchers at University College London.

In the journal "Circulation: Cardiovascular Genetics", the scientists published a study with data from five European research projects. Almost 4,000 women and men participated in the study. By comparing genes, blood vessel health and arterial thickness, physicians were able to identify a specific gene associated with a higher risk of diseased blood vessels, heart attacks and strokes in women.

The heart attack risk in women is significantly influenced by a specific gene. (Image: Kzenon / fotolia.com)

Combination of estrogen and "BCAR1 gene" could be cause
Researchers suggest that the combination of estrogen naturally occurring in women and said gene could increase the risk of heart disease. But much work still needs to be done to fully understand the context. The BCAR1 gene can promote mass migration of cells. This process causes the blood vessel walls to become thicker. Such thick vessel walls can increase the likelihood of blockages that later lead to heart attacks and strokes.

Gen could become the main target of future drugs
It has long been known that the risk factors of heart disease in women and men are different, said the co-author of the study Freya Boardman-Pretty. The BCAR1 gene exerts its effect on the blood vessel walls only in women. This gene could make the big difference. However, there are many other factors to consider that play a role, according to the researcher. If it is confirmed that the gene is involved in an increased risk of heart disease in women and how BCAR-1 has an impact, this could be the basis for the development of new drugs. Freya Boardman-Pretty said that more research is needed here and that all people should generally live as healthy lives as possible to protect themselves from heart disease.

Heart disease is not a typical male disease
Dr. Shannon Amoils of the British Heart Foundation added that heart disease is often considered a typical male disease. However, this is not the case; the victims often also include women. It is urgent that as many women and men as possible take steps to prevent heart problems. They could reduce their risk by not smoking, exercising regularly and exercising. But even a healthy diet leads to better protection against heart disease, says the doctor.