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French fries, pizza or hamburgers A single greasy meal can permanently damage the body
You do not necessarily have to resort to fries, cheeseburgers and pizzas every day to increase your diabetes risk. A single high-fat meal is enough to cause insulin resistance and increase the fat content of the liver, according to a new study.
Saturated fats harm your health
Diet has a big impact on our health. For example, experts advise against the regular consumption of saturated fats, as they affect the general life expectancy. The consumption of such fats is also often associated with the worldwide spread of obesity, obesity and type 2 diabetes. Researchers have now discovered that you do not have to consume too much to damage your health. Even a single high-fat meal can affect your metabolism.
Anyone who regularly consumes pizza, chips and similar foods increases their diabetes risk. Researchers have now found that even a single high-fat meal is enough to cause insulin resistance. (Image: Kitty / fotolia.com) Study reveals the earliest changes in liver metabolism
Scientists at the German Diabetes Center (DDZ) and the Helmholtz Zentrum München have found that even the single intake of a larger amount of palm oil reduces the sensitivity of the body to insulin and causes increased fat storage and changes in the energy metabolism of the liver.
According to a statement by the Helmholtz Center, the study results provide information about the earliest changes in liver metabolism that can lead to long-term fatty liver disease in overweight and type 2 diabetes.
A single high fat meal can cause insulin resistance
In the journal "Journal of Clinical Investigation" the researchers of the German Center for Diabetes Research (DZD) together with Portuguese colleagues published a study on healthy, slim men, who randomly chose a flavored palm oil drink and another time a glass of clear water received.
The palm oil drink contained a similar amount of saturated fat as two cheeseburgers with bacon and a large portion of French fries or two salami pizzas.
The experts showed that this single high-fat meal is sufficient to reduce the insulin action, thus producing insulin resistance and increasing the fat content of the liver.
In addition, changes in the energy balance of the liver could be detected.
The observed metabolic changes are similar to the changes seen in people with type 2 diabetes or non-alcoholic fatty liver disease (NAFLD).
"NAFLD is the most common liver disease in the developed world and associated with obesity, the so-called" metabolic syndrome ", and increased risk of type 2 diabetes. In addition, NAFLD can lead to severe liver damage in advanced stages, "the DDZ said.
Effects on the liver of healthy people
"It was surprising that a single dose of palm oil in healthy people has such a direct and immediate effect on the liver and by the amount of fat already administered an insulin resistance is triggered," said Prof. Dr. med. Michael Roden, Scientific Director and Board Member at DDZ and DZD.
Already in the past, experts have warned about the risks of palm oil in food, pointing out that it should be replaced altogether.
Palm oil affects muscles, liver and adipose tissue
Thanks to new research methods, the scientists proved that the ingestion of palm oil affects muscles, liver and adipose tissue in their metabolic activity.
Thus, the insulin resistance caused leads to an increase in the formation of new sugars in the liver and at the same time reduced sugar uptake in the skeletal muscle, a mechanism which causes the blood sugar level to rise in type 2 diabetes and its precursors.
In addition, the insulin resistance of adipose tissue causes an increased release of fats into the bloodstream, which in turn further promote insulin resistance.
The increased availability of fat leads to increased workload of the mitochondria, which in the long term can overwhelm these cellular power plants and contribute to the development of liver disease.
The team of scientists suspect that healthy people can easily handle the immediate effects of high-fat foods on their metabolism, depending on the predisposition of the genes. However, the long-term consequences for regular eaters of such high-fat meals could be problematic. (Ad)