Herbal anti-diabetes drug discovered

Hope for Diabetes Sick: Herbal drug for diabetes discovered.

Researchers from the "Shanghai Institute of Materia Medica" of the "Chinese Academy of Science" have shown in a series of experiments with mice that the natural plant active ingredient Emodin, which is derived from various Chinese herbs, reduces the effects of type 2 diabetes.

The research team around the specialist Dr. Ying Leng has published his findings in the current issue of the British Journal of Pharmacology and concludes that Emodin, a natural extract from various Chinese herbs, can help people with type 2 diabetes (old-age diabetes) to get sick. Also in other metabolic diseases that are associated with insulin resistance, promises Emodin remedy, so the expert Dr. ling. "Our experiments have shown that this natural extract of Chinese herbs can help people with type 2 diabetes. With this insight, we can develop substances that work in a similar way to Emodin, to a drug, "explained Dr. med. Ling in the British Journal of Pharmacology.

The process scientists use to make Emodin effective is largely due to the function of the enzyme 11-HSD1. 11-HSD1 helps in the human body as an enzyme in the breakdown of glucose to glucocorticoids. Ingesting sugar through food releases insulin and glucocorticoids in the body, which have an opposite effect: insulin breaks down the sugar in the blood, glucocorticoids increase the blood sugar content. Since 11-HSD 1, as an enzyme, promotes the production of glucocorticoids, the blood sugar level does not drop back after food intake as intended. Since diabetics are resistant to insulin and therefore the sugar in the blood can not be broken down, this process is particularly problematic for them. Emodin inhibits the results of the study, the effect of 11-HSD 1, thus reducing the glucocorticoids, lowers the blood sugar content and relieves the symptoms of type 2 diabetes.

For example, when investigating obese mice with type 2 diabetes, the researchers have found a clear positive effect of taking Emodin on blood sugar levels. In addition, her weight and the proportion of body fat was reduced and there was a significant improvement in the blood levels to detect, said Dr. med. Ying Leng on the results of the study. The enzyme 11beta HSD-1, which also occurs in adipose tissue, also influences the production of the stress hormone cortisol, which is responsible for the fat accumulation in the abdominal area, which in turn is considered a particular risk for diabetes and heart disease. (Fp)

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