Researchers present illustration of Zika virus

New findings could explain the accumulation of skull malformations
US scientists have analyzed the finest structures on the envelope of Zika viruses. This could possibly explain why the virus can pass on the infection of pregnant women on fetuses. The new findings are critical to the development of effective antiviral treatments and vaccines, according to a recent release from Purdue University.

Accumulation of cranial deformities in newborns
Researchers at Purdue University in West Lafayette (Indiana) have been able to analyze microscopic structures on the envelope of Zika viruses under the microscope. As the scientists report in the journal "Science", the virus in its structure is largely similar to the dengue pathogen, but has fine structural differences on the shell. These may provide an explanation for why malformations of neonates are common, said study lead author Devika Sirohi, according to the University's report. Because the Zika virus is suspected of infections of pregnant skull malformations in newborn babies (microcephaly) https://www.heilpraxisnet.de/naturheilpraxis/schaedelfehlbildungen-bei-neugeborenen-babys-aengste-vor-dem-zika-virus- going to cause 2015112350252. The children are born with an unusually small head, which can lead to brain malformations. The little ones are often mentally handicapped and suffer from neurological disorders because the brain is underdeveloped.

Image: jarun011 - fotolia

Viruses usually do not enter the nervous system of the fetus
"Most viruses do not enter the nervous system or the developing fetus because of the blood-brain barrier and the blocking capsule," says Devika Sirohi. The connection with the faulty brain development, however, give an indication that the Zika virus this could. "It is not clear how Zika gains access to and infects these cells, but these structurally different areas could be involved. These unique areas can be critical and justify further investigation, "the expert continued.

Virus is rife in more than 30 countries
The Zika virus is currently causing great concern worldwide. Especially in South and Central American countries, it is spreading steadily, currently more than 30 countries are affected. Recently, a massive spread of the Zika virus in Colombia has become known, where, according to authorities, so far more than 2,000 pregnant women have been infected. In twelve of the countries concerned, an increased incidence of the so-called "Guillain-Barré syndrome" is evident, Brazil and French Polynesia have also registered a significant increase in microcephaly, the researchers said, citing WHO

"Determining the structure means progress in our understanding of Zika - a virus about which little is known. It sheds light on the most promising areas for further testing and research to combat the infection, "said Richard Kuhn of Purdue University. Mitch Daniels said the research team had "solved a very difficult puzzle" within a remarkably short time, paving the way for the development of vaccines and treatments, the report says. (No)