Ovarian tissue successfully retransplanted

Ovarian tissue successfully retransplanted - child born naturally

13/09/2012

For the second time, researchers from Erlangen have achieved great success after the retransplantation of frozen ovarian tissue. A woman suffering from breast cancer four years ago, thanks to the procedure, gave birth naturally to a child a few days ago.

Ovarian tissue was frozen before chemotherapy
After a young Nuremberg suffered in 2008 from breast cancer, she was taken from ovarian tissue and freeze, as threatened by the then upcoming chemotherapy infertility. Already two years after the treatment, the frozen tissue was thawed in the University Hospital Erlangen and in August 2011 finally fully functional back transplanted. „A few days ago the woman became a happy mother. So far 13 times worldwide it has been possible for a woman who has been infertile to give birth to a child by natural means following the retransplantation of her cryopreserved ovarian tissue“, reported the hospital in a recent press release.

Klaus Diedrich, former director of the Clinic for Obstetrics and Gynecology of the University Hospital in Lübeck assessed the success of Erlangen researchers restrained. Ovarian tissue can also get naturally after cancer treatment, explained Diedrich, who was also president of the German Society for Gynecology and Obstetrics (DGGG), to the news agency „dpa“. However, it was a good medical solution, provided the information from Erlangen was correct. The chances are „50 to 50“, that the success was due to tissue that has regenerated after chemotherapy. Diedrich sees the method - if it was actually successful - in the future also in the field „social freezing“, Tissue is harvested from older women to meet the desire to have children at a later date.

Only 13 births after ovarian tissue retransplantation worldwide
The Erlangen Gynecological Clinic has been researching the retransplantation of ovarian tissue for about ten years. In 2008, for the first time in Germany, physicians successfully retransplanted frozen ovarian tissue to a former breast cancer patient. „In 2011, the Erlangen Reproduction Physicians, in cooperation with the University Clinics in Dresden and Bonn, succeeded in retransplanting ovarian tissue so that a former lymph node cancer patient naturally became pregnant and was released by cesarean section in October 2011 in Dresden“, it says in the press release of the hospital. This procedure was now successful for the first time in a former breast cancer patient. In the case of the young Nuremberger, the entire therapy took place in the Erlangen Reproduction Center.

The ovarian tissue retransplantation has been carried out in Erlangen since 2007 in eleven women. Although the method failed with no patient, only two children were born. Worldwide, this has only been achieved 13 times, as the Erlangen Clinic reports. (Ag)

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