Outsmarting DNA Will a simple syringe help you lose weight in the near future?

In the future, overweight people could be helped to lose weight with a syringe
Researchers have found that certain genes play a key role in the development of obesity. They also found that metabolism can be revved up with a DNA change. In the future, an injection might help you lose weight.

Losing weight with the "DNA trick"
People who weigh too many kilos are always trying to lose weight. Most of them then torture themselves - often unsuccessfully - with different diets. Often it is not at all clear whether it would be better to eat less fat or less carbohydrates, but to generally eat less and healthier and to move more. However, it may be easier for some people to get rid of extra pounds in the future. The "Berliner Kurier" reports on his Internet portal about a new "DNA trick" that could help you lose weight.

By interfering with the DNA, fat burning can be stimulated. (Image: Piotr Wawrzyniuk / fotolia.com)

Genes responsible for severe overweight
Thus, an injection might soon be enough to reduce the weight. Researchers at the US universities Harvard and MIT (Massachusetts Institute of Technology) and the Munich Technical University (TU) have found that you get the metabolism with a small DNA change back to full speed. The scientists found in their studies that in humans with obesity the two genes IRX3 and IRX5 are "turned on", but not in normal weight people. When the genes were turned off again, the cells burned fat and produced heat. An international team of researchers had reported last year that they had found out in experiments with mice that the IRX3 gene is significantly responsible for obesity.

Hope for anti-obesity drugs
As the "Berliner Kurier" writes, so far the so-called FTO gene had been regarded as the most important candidate for obesity. "Many studies have attempted to link FTO to areas of the brain that control appetite," Dr. Melina Clausnitzer, Nutritionist at the Technical University of Munich. The expert compared the now successful decryption with the investigation of a crime: "The main suspect FTO is in fact not the actual culprit. Our methods were now able to convict two perpetrators, IRX3 and IRX5, who were not initially under suspicion. "Her colleague Professor Manolis Kellis of MIT expressed his confidence:" After recognizing these relationships, we could switch back and forth between energy storage and combustion and hope that we can use it to find a remedy for obesity. "In Germany, about every third adult is considered to be severely overweight. Obesity and its precedence, being overweight, are often the cause of sequelae such as high blood pressure, coronary heart disease, type 2 diabetes or cancer. (Ad)