26 different antibiotics did not work Patient dies from resistant germs

26 different antibiotics did not work Patient dies from resistant germs / Health News
Multidrug-resistant germ: patient died after unsuccessful treatment with 26 antibiotics
In the US, one patient died of an infection because none of the approved 26 antibiotics could help her. Resistant germs are a major threat to human health. If treatment with antibiotics is no longer possible, even small inflammations can be a big risk.


Millions of deaths feared by multi-resistant germs
The increase in antibiotic resistance is posing an ever-increasing challenge for healthcare professionals. If the problem is not brought under control soon, according to researchers threatens a horror scenario. According to an earlier study by the Berlin Charité, there could be around 10 million deaths from multidrug-resistant germs by 2050. From the United States is now reported on the case of a woman in which none of the 26 applied antibiotics showed effect. The patient died.

In the US, one patient died of an infection after all 26 approved antibiotics had shown no effect. The mass use of such drugs promotes resistance. (Image: nenetus / fotolia.com)

All 26 approved antibiotics were ineffective
Last year, an EU commission warned against massively increasing antibiotic resistance.

An estimated 700,000 people are already dying every year from infections caused by pathogens that are not medicated.

Even for a patient in the US, there was no help. According to a news agency AFP, the woman died of an infection after all 26 approved antibiotics had had no effect.

Multidrug resistant Klebsiella pneumoniae germ
According to the CDC, the CDC found that the retiree had a multidrug-resistant Klebsiella pneumoniae germ that could not be effectively treated with antibiotics.

Such pathogens are increasingly worrying experts, as they make infections incurable. According to the CDC, the woman ultimately died of blood poisoning.

According to AFP, in recent years she has often been in India, where she has been treated for a fractured femur. In September, she died at the isolation ward at the Nevada hospital, where she eventually arrived. All 26 US-approved antibiotics did not help the patient.

"Urgent danger to human health"
The World Health Organization (WHO) has classified the Klebsiella pneumoniae germ as an "urgent threat to human health".

The mortality rate in people who are infected with this bacterium is according to experts at 40 to 50 percent. There are more and more pathogens found that are resistant to antibiotics. For a long time experts have warned that in a post-antibiotic era, even mild illnesses in weakened patients could lead to death.

Super pathogen immune to all treatment methods
In the USA, a so-called super-pathogen was first discovered last May, which is immune to all known treatment methods. At that time, a 49-year-old from the state of Pennsylvania had been found in a urinary tract infection, an E-coli bacterium against which no antibiotic had helped. The "super-pathogen" was even immune to the emergency antibiotic Colistin immune.

But the woman survived. According to AFP, the bacterium contained a gene that makes it immune to antibiotic treatment for multidrug-resistant bacteria. In the now deceased in Nevada patient, the so-called Mcr-1 gene was not found.

The autopsy revealed that she may have been helped with the antibiotic fosfomycin. However, this is not allowed in the US.

Especially in the hospital area a problem
Especially in the hospital sector multiresistant pathogens (MRE) are a growing problem worldwide.

According to the Federal Ministry of Health, 400,000 to 600,000 patients worldwide contract hospital infections each year. 10,000 to 15,000 people die every year. Other experts estimate the case numbers higher.

For example, the German Society for Hospital Hygiene (DGKH) estimates that there are almost one million infections and at least 30,000 deaths.

Reduce mass use of antibiotics
"Inpatient and outpatient treatment and care are associated with a risk of infection," writes the Robert Koch Institute (RKI) on its website. If more hospitals were to comply, the risk could be significantly reduced. But about every fourth clinic passes important hygiene regulations.

Probably the most important point in the fight against antibiotic resistance is to reduce the mass use of such drugs.

Because the excessive use of antibiotics in humans and in animal feed and improper ingestion of drugs promotes resistance. (Ad)